Common Subject Communication Challenges

• Forgotten Study Visits

• Non-Compliance (Medication Adherence)

• Misunderstood Expectations/Information

• Motivation

• Inefficient Communications

• Lack of Feeling Appreciated

Solutions Using Automated Text Messaging

• Reminders for Dosing, Samples and Activities

• Appointment Reminders

• Information Delivered in Real-Time

• Positive Messaging, Incentives

• Automated Messaging and Responders

• Improve Patient-Centricity

Mobile Apps Are Not the Answer

Mobile app management is a problem creating unnecessary stressors for site staff.

• Discoverability (100,000 mHealth apps in the app store)

• Device Variation (108 mobile phone brands, hundreds of types)

• Operating Systems (22 mobile operating systems currently)

• Version Control (27 different version of Android alone)

Text Messaging is Ubiquitous Worldwide

Subjects use the mobile channel they prefer: text messaging.

• 98% of mobile phones have text messaging.

• It’s the “app” on nearly every mobile phone.

• Text messaging is the number one data service in the world.

Email and phone calls are not as effective for engagement

• 23% of phone calls go straight to voicemail.

• 80% of people don’t answer calls from unknown numbers.

• 30% of voicemails linger unheard for 3 days or longer.

• 90% of emails are spam.

Texting enables subjects to use their own mobile devices.

• 91% of mobile users keep phones within arm’s reach 24/7.

• 90% of text messages are opened and read within 3 minutes.

• Text messaging is the most-used channel on mobile phones.

With Mosio, there are no apps to download and no device “tech support” requirements by research staff.

Benefits to Clinical Trial Sponsors

Improved Adherence and Compliance

• Reminders for dosing, sample collection and required actions.

• Improve site visit and appointment attendance.

• ePRO link delivery with “nudge” completion reminders.

Efficient Communications for Subjects and Site Staff

• Automated messages and reminders.

• Easy subject enrollment for study staff.

• Pre-scheduled coordinator check-ins to improve engagement.

BYOD (Bring Your Own Device)

• Cost efficient, no phones to provision.

• User friendly, patients know how to use their own phones.

• Accessible to everyone on every mobile device.

FDA 21 CFR Part 11 and HIPAA Compliant

Mosio is compliant to FDA 21 CFR PART 11 along with supplemental documents:
– Guidance For Industry Part 11, Electronic Records; Electronic Signatures — Scope and Application
– Guidance for Industry Computerized Systems Used in Clinical Investigations.

Mosio meets the needs of clients and regulation in critical specified areas such as: role based limited access, validation, data protection, data retrievability, audit trials, date/time stamps, and system training documentation. Data backup and production systems are in geo-diverse locations for added protection. Mosio adheres to a defined SDLC and Quality Policy for ongoing updates and customer support.

HIPAA
Hosted on HIPAA-compliant servers. All data collected by the Mosio platform (PHI or non-PHI) receives the same safeguards for security, privacy and breach notification applied to our clients covered under HIPAA rules and stipulated by a client BAA.

Dosing and Medication Adherence Reminders

Keep tight dosing schedules and ensure desired actions are completed.

Medication adherence or compliance reminders help subjects stay “on task” with protocol requirements.

Ensure Subjects are Informed and Compliant

• Reminder and confirmation of dosage administration.

• Recording of taken and missed doses.

• Tracking of other medications being taken.

• Guides or instructions on taking medications properly.

• Code phrase messaging for privacy.

• Quick access to helpful information.

Appointment Reminders

Fix your “no show” rate with automated text message appointment reminders.

Friendly Reminders with Confirmation

• Merge Field™ technology enables you to inject custom details in the message.

• Schedule single appointments or in batches.

• “Nudge” reminders can be sent for non-responses.

• Notifications to study staff when cancellations occur for quick rescheduling.

“The solution offered unprecedented benefits in operational efficiency including a 91.6% reduction in resources used to remind patients of their study screening visits, and an ability to optimize study screening department resources because of visit confirmations.”
– Quintiles Case Study (published in Applied Clinical Trials)

Improve Patient-Centricity

Support, encourage and motivate.
Automated coordinator check-ins are the perfect way to keep subjects engaged without additional work required from study staff. For example, monthly messages can be pre-scheduled and personalized using a study coordinator’s name, automating outreach.

Benefits to Subjects and Sites:

• Improve the feeling of value by showing subject appreciation.

• Automate study coordinator outreach to increase engagement and reduce workload.

• Keep subject contact information up to date.

Global Reach for International Clinical Trials

Mosio’s network of mobile messaging providers covers the world. We’re able to send text messagings to any country in the world with two-way text messaging capabilities in 50+ countries.

Connect with Third Party Software and Devices

Mosio has a library of over 50 APIs enabling it to integrate with external EDC, ePRO or devices. Contact us for more information about how you can leverage the power of text messaging in your clinical trials, accessible to every study subject.